The tumor microenvironment (TME) plays an essential role in the development, growth, and survival of the malignant B-cell clone in chronic lymphocytic leukemia (CLL).Within the proliferation niches of lymph nodes, bone marrow, and secondary lymphoid organs, a variety of phenotypically and functionally altered cell types, including T cells, natural
Nicotinamide adenine dinucleotide (NAD+/NADH) along with its phosphorylated form (NADP+/NADPH) are two molecules ubiquitously present in all organisms, and they play key roles as cofactors in fundamental catabolic and anabolic processes, respectively.The oxidation of NADPH to NADP+ initiates a cascade of reactions, where a network of molecules is i
In this work, the main trends in research and publication activity in digital transformation in the world and Ukraine are analyzed using meta- and bibliometric analysis.For this purpose, bibliometric data on scientific publications on the topic of digital transformations in the Google Scholar and Scopus databases were selected, which were additiona
Abstract Sinistral portal hypertension, also known as left-sided portal hypertension, is a rare cause of gastric variceal bleeding which occurs secondary to occlusion Jars of the splenic vein.We present a case of venous occlusion and sinistral portal hypertension secondary to distal pancreatic cancer requiring treatment of gastric variceal bleeding